Activator Protein-1

Description

Activator protein-1 (AP-1) is a transcription factor heterodimer consisting of the proteins FosB (pictured as dark green) and JunD (light green). The heterodimer is assembled in a Basic Leucine Zipper Domain (bZIP). AP-1 regulates gene expression controlling cellular differentiation, proliferation, and apoptosis. The model shows AP-1 bound to DNA.